Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
NOT YET RECRUITING
NCT07773740
NA

Autologous Plasma Rich in Growth Factors for Severe Dry Eye Disease

Sponsor: Gladys Lucia Silva Linares

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to evaluate the change in dry eye symptoms after the treatment with Plasma Rich in Growth Factors (PRGF) in patients with severe dry eye. The main question it aims to answer is: Are dry eye simptoms less after the treatment with PRGF? Researchers will compare standard topical treatment and PRGF with standard topical treatment and placebo to see if there is a difference in dry eye symptoms between arms. Secondary outcomes include changes in tear meniscus height, non invasive tear break-up time, conjunctival hyperemia, meibomian gland dropout and Ocular Staining Score (OSS) scale for corneal and conjunctival damage. Participants will be asked to use standard treatment and PRGF or placebo for 1 month.

Official title: Impact of Treatment With Autologous Plasma Rich in Growth Factors (PRGF) in Patients With Severe Dry Eye Disease.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2026-08-25

Completion Date

2027-08

Last Updated

2026-08-25

Healthy Volunteers

No

Interventions

OTHER

PRGF

PRGF eyedrops four times a day for 1 month

OTHER

Balanced Salt Solution (BSS®)

Balanced salt solution 0.09% eyedrops four times a day for 1 month