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FABP4 Response After Roux-en-Y Gastric Bypass
Sponsor: Istanbul University
Summary
This retrospective observational cohort study examined serum fatty acid-binding protein 4 (FABP4) dynamics in 28 adults who underwent Roux-en-Y gastric bypass (RYGB), followed at baseline, 3 months, and 6 months. Anthropometric, metabolic, and inflammatory parameters were assessed alongside FABP4, fasting GLP-1, and PYY. Patients were classified as FABP4 responders (decrease from baseline to 6 months) or rebound/non-responders. The study investigated whether FABP4 trajectory after RYGB is associated with the magnitude of weight loss, systemic inflammation, and fasting incretin change.
Official title: Heterogeneous Fatty Acid-Binding Protein 4 (FABP4) Responses After Roux-en-Y Gastric Bypass: A Retrospective Observational Cohort Study of Adipokine Remodeling Dissociated From Weight Loss, Inflammation, and Incretin Dynamics
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
OBSERVATIONAL
Enrollment
28
Start Date
2013-04-22
Completion Date
2015-02-10
Last Updated
2026-08-19
Healthy Volunteers
No