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Dietary Interventions for Irritable Bowel Syndrome
Sponsor: Istanbul Gelisim University
Summary
Irritable bowel syndrome (IBS) is a disorder of gut-brain interaction characterized by recurrent abdominal pain and altered bowel habits. Dietary factors may trigger or worsen symptoms such as abdominal pain, bloating, gas, diarrhea, and constipation. This study evaluated and compared the effects of a low-fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (low-FODMAP) diet and a combined gluten-free and lactose-free diet on symptom severity in adults diagnosed with IBS. Adults aged 19-64 years with IBS followed one of the two dietary interventions for six weeks. IBS symptom severity was assessed at baseline and at the end of week 6 using the Irritable Bowel Syndrome Symptom Severity Score (IBS-SSS). Dietary adherence was monitored by telephone during the intervention.
Official title: The Effects of a Low-FODMAP Diet and Gluten-Free and Lactose-Free Dietary Interventions on Symptoms in Patients Diagnosed With Irritable Bowel Syndrome
Key Details
Gender
All
Age Range
18 Years - 64 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2025-02-25
Completion Date
2025-07-18
Last Updated
2026-08-20
Healthy Volunteers
No
Conditions
Interventions
Low-FODMAP Diet
Participants followed a low-FODMAP diet for six weeks. Foods high in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols were restricted. Participants received detailed dietary instructions during the initial face-to-face visit. Dietary adherence was monitored by telephone one week after starting the intervention and subsequently at two-week intervals.
Gluten-Free and Lactose-Free Diet
Participants followed a combined gluten-free and lactose-free diet for six weeks. Foods containing gluten and lactose were excluded. Participants received detailed dietary instructions during the initial face-to-face visit. Dietary adherence was monitored by telephone one week after starting the intervention and subsequently at two-week intervals.
Locations (1)
Mersin University Hospital
Mersin, Turkey (Türkiye)