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Substance Use in Pregnancy - Optimizing Retention in Treatment by Maximizing Opportunities for Management
Sponsor: Washington University School of Medicine
Summary
Overdose is a national top-three leading cause of pregnancy-associated death, and maternal substance use disorder (SUD) accounts for an estimated $1.5 billion in healthcare spending each year. Treatment with medication and behavioral therapy lowers morbidity and overdose risk. However, studies have shown 55% to 80% of patients stop treatment within one year postpartum. Additionally, as a result of systemic inequities, historically marginalized patients are at greatest risk of overdose or death. We are conducting a study at WashU Medicine and University of Maryland, Baltimore clinics that offer prenatal care, addiction treatment, and extended postpartum support for patients facing the challenges of a SUD. Study participants will complete a structured screening and management of their social needs, and then will be randomly assigned to continue their usual care or to participate in a contingency management program, which provides incentives to continue treatment.
Official title: Substance Use in Pregnancy- Optimizing Retention in Treatment by Maximizing Opportunities for Management
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
245
Start Date
2027-01
Completion Date
2030-02
Last Updated
2026-08-20
Healthy Volunteers
No
Conditions
Interventions
Contingency Management
12 weekly sessions, 15-20 minutes each
Social Drivers of Health Screening
Screening for social drivers of health, documentation of applicable z-codes in the medical record and social needs linkage
Locations (1)
Washington University
St Louis, Missouri, United States