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NOT YET RECRUITING
NCT07776457
PHASE2

Substance Use in Pregnancy - Optimizing Retention in Treatment by Maximizing Opportunities for Management

Sponsor: Washington University School of Medicine

View on ClinicalTrials.gov

Summary

Overdose is a national top-three leading cause of pregnancy-associated death, and maternal substance use disorder (SUD) accounts for an estimated $1.5 billion in healthcare spending each year. Treatment with medication and behavioral therapy lowers morbidity and overdose risk. However, studies have shown 55% to 80% of patients stop treatment within one year postpartum. Additionally, as a result of systemic inequities, historically marginalized patients are at greatest risk of overdose or death. We are conducting a study at WashU Medicine and University of Maryland, Baltimore clinics that offer prenatal care, addiction treatment, and extended postpartum support for patients facing the challenges of a SUD. Study participants will complete a structured screening and management of their social needs, and then will be randomly assigned to continue their usual care or to participate in a contingency management program, which provides incentives to continue treatment.

Official title: Substance Use in Pregnancy- Optimizing Retention in Treatment by Maximizing Opportunities for Management

Key Details

Gender

FEMALE

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

245

Start Date

2027-01

Completion Date

2030-02

Last Updated

2026-08-20

Healthy Volunteers

No

Interventions

BEHAVIORAL

Contingency Management

12 weekly sessions, 15-20 minutes each

OTHER

Social Drivers of Health Screening

Screening for social drivers of health, documentation of applicable z-codes in the medical record and social needs linkage

Locations (1)

Washington University

St Louis, Missouri, United States