Clinical Research Directory

Inclusion Criteria: 1. Age 21-80 years old; 2. First ever stroke, at least 9 months after stroke onset; 3. Evidence of corticomotor excitability as manifested by a recordable Motor Evoked Potential from the ipsilesional Motor Cortex (M1) by TMS measurement. 4. Objectively documented motor weakness of the upper extremity as manifested by an Upper Extremity-Fugl-Meyer Assessment score \<=55 Exclusion Criteria: 1. Patients with implants: cardiac, neural or medication implants; any electrically, magnetically or mechanically activated implant; brain medical devices; vascular clips or any other electrically sensitive support system in the brain; other metal implants inside the body that are contraindications of MRI scan; 2. Pregnancy; 3. Patients with a history of seizures; Patients with unexplained episodes of loss of consciousness, since such condition could be related with brain alterations or epilepsy; 4. Patients with serious brain injury; 5. Patients showing damage of skin at sites of stimulation; 6. Patients with unstable or non-controlled neuropsychiatric illness; 7. Patients suffering from severe or frequent headaches; 8. Patients with any serious life-threatening disease such as congestive heart failure, pulmonary obstructive chronic disease or active neoplasia; 9. Sensorimotor disturbance due to other causes other than stroke;