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Alcohol, Breast Cancer, and Metabolism
Sponsor: University of Illinois at Urbana-Champaign
Summary
Alcohol consumption, even at low levels, has been associated with increased breast cancer risk, but the biological mechanisms underlying this relationship remain unclear. This study will examine whether breast tissue may locally metabolize alcohol by measuring alcohol-related compounds in paired blood and breast milk samples from lactating women. The findings may help clarify alcohol-related biological pathways relevant to breast cancer risk and improve risk communication.
Official title: Localized Mammary Alcohol Metabolism as a Mechanism Linking Low-Level Alcohol Intake to Breast Cancer Risk
Key Details
Gender
FEMALE
Age Range
21 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2026-07-27
Completion Date
2032-03-01
Last Updated
2026-08-21
Healthy Volunteers
Yes
Interventions
Low-alcohol level exposure
Participants will consume a protocol-specified low-level alcohol exposure under study conditions. The assigned dose and biospecimen collection procedures will vary by study group.
Breast-pumping time
Breast pumping before or after drinking \~ 1 standard drink