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ENROLLING BY INVITATION
NCT07781514
NA

Vitamin E Add-On Therapy, Thyroid Function & Oxidative Stress in Levothyroxine-Treated Hypothyroidism

Sponsor: Bangladesh Medical University

View on ClinicalTrials.gov

Summary

The aim of this study is to learn if vitamin E supplementation as an adjunct to levothyroxine therapy help to reduce oxidative stress, improve antioxidant defence mechanisms, and favourably influence thyroid hormone status, making it a promising therapeutic strategy for patients with hypothyroidism. The findings from this investigation aim to establish an evidence-based framework for integrating targeted antioxidant therapies into standard hypothyroid management strategies.

Official title: Effect of Vitamin E as add-on Therapy on Thyroid Function and Oxidative Stress in Levothyroxine Treated Hypothyroid Patients: A Randomized, Double-blind, Placebo-controlled Trial

Key Details

Gender

All

Age Range

18 Years - 75 Years

Study Type

INTERVENTIONAL

Enrollment

74

Start Date

2027-02

Completion Date

2027-07

Last Updated

2026-08-25

Healthy Volunteers

No

Conditions

Interventions

DIETARY_SUPPLEMENT

vitamin E

participants received vitamin E 400mg capsule orally once daily for 12 weeks

DIETARY_SUPPLEMENT

placebo

participants received vitamin E placebo orally once daily for 12 weeks

Locations (1)

Bangladesh Medical University

Dhaka, Bangladesh