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Neurophysiological and Autonomic Responses to Acute Physical and Emotional Stress: An EEG Study
Sponsor: University of Pavia
Summary
This study aims to investigate neurophysiological, autonomic, and subjective responses to different acute physical and emotional stress-inducing conditions using a within-subject repeated-measures design. Participants will complete four experimental conditions: a resting-state baseline, a Cold Pressor Test, a negative autobiographical memory recall task, and an affective picture-viewing task using stimuli selected from the Nencki Affective Picture System (NAPS). The order of the experimental stress conditions will be randomized or counterbalanced to minimize potential order and carry-over effects. Electroencephalographic (EEG) and autonomic activity will be recorded throughout the experimental session. Autonomic measures will include heart rate (HR), heart rate variability (HRV), electrodermal activity (EDA), and skin conductance responses (SCR). Subjective levels of stress, anxiety, and pain will be assessed using visual analogue scales (VAS). Participants will also complete validated psychological measures assessing resilience, perceived stress, and state and trait anxiety, together with the Tower of London task as a behavioral measure of executive planning. The primary objective is to characterize the modulation of EEG alpha-band activity during acute physical stress, with the main comparison focusing on the Cold Pressor Test relative to resting-state baseline. Secondary and exploratory objectives include comparing cortical, autonomic, and subjective responses across experimental conditions and investigating whether individual psychological characteristics and executive functioning are associated with differences in psychophysiological stress responses.
Official title: Electrophysiological, Autonomic, and Psychological Responses to Acute Physical and Emotional Stress: A Within-Subject Experimental EEG Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2026-08-01
Completion Date
2026-08-15
Last Updated
2026-08-24
Healthy Volunteers
Yes
Conditions
Interventions
Cold Pressor Test
Participants will immerse one hand in an ice-water bath and will be instructed to maintain the immersion for as long as tolerable, up to a maximum of three minutes. Participants may withdraw their hand at any time if the stimulation becomes intolerable. The actual duration of hand immersion will be recorded as an index of pain tolerance. EEG and autonomic activity will be continuously recorded during the task.
Negative Autobiographical Memory Recall
Participants will be instructed to select a personally painful or distressing autobiographical memory and focus on its emotional and experiential aspects for three minutes while seated with their eyes closed. No specific autobiographical event will be suggested by the researcher. EEG and autonomic activity will be continuously recorded during the task.
Affective Picture-Viewing Task
Participants will view negative and neutral images selected from the Nencki Affective Picture System (NAPS). Each trial will consist of a 10-second fixation period followed by a 30-second image presentation. Images will be presented in randomized order while EEG and autonomic activity are continuously recorded.
Locations (1)
University of Pavia
Pavia, Lombardy, Italy