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Effect of Different Volumes of SPSIP Block in Breast Surgery
Sponsor: Bursa City Hospital
Summary
This randomized, double-blind study will compare the effectiveness of three different volumes of serratus posterior superior intercostal plane block for postoperative pain control in patients undergoing unilateral breast surgery with axillary lymph node dissection. Ninety participants will be randomly assigned to receive 20 mL, 30 mL, or 40 mL of 0.25% bupivacaine. The primary outcome is total tramadol consumption during the first 24 hours after surgery. Pain scores, time to first analgesic request, rescue analgesic use, quality of recovery, postoperative nausea and vomiting, block success, and block-related complications will also be evaluated.
Official title: Effectiveness of Serratus Posterior Superior Intercostal Plane Block Administered With Different Volumes of 0.25% Bupivacaine for Postoperative Analgesia in Breast Surgery: A Prospective, Randomized, Double-Blind Study
Key Details
Gender
FEMALE
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
90
Start Date
2026-03-15
Completion Date
2027-02-15
Last Updated
2026-08-24
Healthy Volunteers
No
Conditions
Interventions
Bupivacaine 0.25% (20 mL)
A single ultrasound-guided serratus posterior superior intercostal plane block will be performed before general anesthesia using 20 mL of 0.25% bupivacaine. The local anesthetic will be injected between the serratus posterior superior and intercostal muscles at the T3-T4 level.
Bupivacaine 0.25% (30 mL)
A single ultrasound-guided serratus posterior superior intercostal plane block will be performed before general anesthesia using 30 mL of 0.25% bupivacaine. The local anesthetic will be injected between the serratus posterior superior and intercostal muscles at the T3-T4 level.
Bupivacaine 0.25% (40 mL)
A single ultrasound-guided serratus posterior superior intercostal plane block will be performed before general anesthesia using 40 mL of 0.25% bupivacaine. The local anesthetic will be injected between the serratus posterior superior and intercostal muscles at the T3-T4 level.
Locations (1)
Bursa City Hospital
Nilufer, Bursa, Turkey (Türkiye)