Clinical Research Directory
Browse clinical research sites, groups, and studies.
CEST for Prostate Biopsy
Sponsor: Sunnybrook Health Sciences Centre
Summary
Samples of prostate tissue acquired by biopsy to determine whether there is cancer will sometimes not find cancer that is present. Conventionally, magnetic resonance imaging (MRI) is used to identify 12 areas to biopsy. We will use an advanced MRI method called magnetization transfer (MT) and chemical exchange saturation transfer (CEST) imaging to suggest two additional biopsy location. Our objectives are to determine 1) whether MT/CEST MRI can aid in the detection prostate cancer and 2) whether MT/CEST MRI can aid conventional MRI in risk stratification and to decide whether targeted prostate biopsy is justified.
Official title: Advanced Metabolic MRI to Refine Targeted Prostate Biopsy
Key Details
Gender
MALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2026-09
Completion Date
2027-09
Last Updated
2026-08-25
Healthy Volunteers
No
Conditions
Interventions
Biopsy-Guided Therapy Selection
Saturation transfer MRI (chemical exchange saturation transfer and magnetization transfer) used to identify two additional biopsy locations in addition to those identified by conventional MRI.
Locations (1)
Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada