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NOT YET RECRUITING
NCT07786090

Mechanistic 129 Xe MRI Study to Assess Therapeutic Response in Fibrotic Interstitial Lung Disease

Sponsor: Dr. Grace Parraga

View on ClinicalTrials.gov

Summary

The goal of this observational study is to better understand how treatment affects the lungs of adults (ages 18-80) with fibrotic interstitial lung diseases. The main questions it aims to answer are: * Can advanced imaging detect the effect of currently approved therapies on people with fibrotic interstitial lung diseases? * What is the relationship between the response to therapy and the imaging response to therapy?

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

OBSERVATIONAL

Enrollment

35

Start Date

2026-11

Completion Date

2029-01

Last Updated

2026-08-25

Healthy Volunteers

No

Interventions

OTHER

Hyperpolarized 129Xe MRI

Inhalation of hyperpolarized 129Xe gas followed by breath-hold MRI for ventilation imaging.

Locations (1)

Robarts Research Institute; The University of Western Ontario; London Health Sciences Centre

London, Ontario, Canada