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Optimizing Lymphatic Pumping for Influenza Vaccine Responses in Vulnerable Populations
Sponsor: Lake Erie College of Osteopathic Medicine
Summary
We are studying if a specific osteopathic manipulative treatment protocol can improve the immune response (antibody titers) to seasonal influenza vaccination in vulnerable populations, including patients with advanced age and/or adiposity.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2026-09
Completion Date
2027-10
Last Updated
2026-08-26
Healthy Volunteers
Yes
Conditions
Interventions
Osteopathic Manipulation
In this intervention, participants will receive 5 minutes of thoracic inlet myofascial release 2 days prior to influenza vaccination, the day of influenza vaccination and 4 days post-influenza vaccination.
Osteopathic manipulation
In this intervention, participants will receive osteopathic manipulation 2 days prior to influenza vaccination, the day of influenza vaccination, and 4 days post-influenza vaccination. The OMT will include thoracic inlet myofascial release, pectoral traction, rib raising, doming of the diaphragm, pelvic diaphragm release, popliteal fossa release, plantar myofascial release, passive Miller thoracic pump, liver pump, and spleen pump.
Sham
In this intervention, participants will receive no osteopathic treatments
Locations (1)
Plaza 38 Medical Offices
Erie, Pennsylvania, United States