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Assessing the Short-Term Effects of Multi-Fiber Supplementation on Gut Health
Sponsor: Brown University
Summary
This is a randomized, parallel-group interventional study evaluating the short-term gastrointestinal effects of a standardized multi-fiber supplement in healthy adults. Approximately 100 participants (50 per arm) aged 18 and older will be randomized to receive either the multi-fiber supplement or a control (flavoring agent only) daily for 10 days. Objectives include assessing effects on stool characteristics, specifically frequency and consistency, as well as changes in metagenomically inferred short-chain fatty acid production potential from the microbiota. Eligible participants must be free of chronic disease, acute illness, and recent antibiotic, probiotic, or prebiotic use. Total participation duration is 10 days.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2026-08
Completion Date
2029-08
Last Updated
2026-08-26
Healthy Volunteers
Yes
Interventions
Prebiotic
Formulated prebiotic supplement designed to be accessible to gut microbiota members and assist with bowel movement regularity
Placebo
Placebo supplementation intervention, with only flavoring agents and no prebiotic fiber
Locations (1)
Biomedical Center
Providence, Rhode Island, United States