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NOT YET RECRUITING
NCT07787286
NA

EMS vs. Resistance Training in Overweight Women

Sponsor: Birjand University of Medical Sciences

View on ClinicalTrials.gov

Summary

This study aims to compare the effects of eight weeks of resistance training versus electrical muscle stimulation (EMS) on oxidative stress indicators and cellular health index in overweight and obese women aged 35-45 years. Forty-two participants will be randomly assigned to three groups: resistance training, EMS, and control. The resistance training group will perform progressive resistance exercises three times per week for eight weeks. The EMS group will receive electrical muscle stimulation on biceps, abdominal, back, and quadriceps muscles three times per week for eight weeks. The control group will receive no intervention. Oxidative stress markers including superoxide dismutase (SOD), glutathione peroxidase (GPX), catalase (CAT), glutathione, protein carbonyl (PC), and total antioxidant capacity (TAC) will be measured from blood samples. Cellular health will be assessed using phase angle (PhA) derived from bioelectrical impedance analysis. Upper and lower body muscular strength and endurance will also be evaluated. All measurements will be taken at baseline and 48 hours after the last training session. The primary outcome is change in phase angle. Secondary outcomes include changes in oxidative stress markers and physical performance.

Official title: Comparison of the Effect of Eight Weeks of Electrical Muscle Stimulation (EMS) Versus Resistance Training on Oxidative Stress Indicators and Cellular Health Index in Overweight and Obese Women

Key Details

Gender

FEMALE

Age Range

35 Years - 45 Years

Study Type

INTERVENTIONAL

Enrollment

42

Start Date

2026-09-15

Completion Date

2026-11-25

Last Updated

2026-08-26

Healthy Volunteers

Yes

Interventions

OTHER

Resistance Training

Progressive resistance training program including upper body (chest press), back (lat pulldown), abdominal (crunch), and lower body (squat) exercises. Performed 3 times per week for 8 weeks. Each session includes warm-up (10 min), main exercises (30 min), and cool-down (10 min). Intensity: 60-85% of 1RM, progressing weekly.

DEVICE

Electrical Muscle Stimulation

Electrical muscle stimulation applied to biceps brachii, abdominals, back, and quadriceps muscles using a commercial EMS device. Parameters: frequency 35-70 Hz, pulse duration 100 μs, pulse period 50 ms, electrode size 150 × 240 mm. Performed 3 times per week for 8 weeks, 15 minutes per session. Intensity progressively increased based on participant tolerance.

OTHER

No Intervention

Participants in the control group receive no exercise intervention during the 8-week study period.

Locations (1)

Faculty of Sport Sciences, University of Birjand

Birjand, South Khorasan Province, Iran