Clinical Research Directory

Inclusion Criteria: Participants must meet all of the following criteria: * Female, age 40 to 54 years. * Recently initiated GLP-1 receptor agonist (GLP-1RA) therapy within the past 6 months. * Body mass index (BMI) ≥27 kg/m². * Not currently participating in regular resistance training (self-reported absence of regular resistance training during the previous month). * Able to stand, sit, and perform bodyweight movements without assistive devices. * Owns a compatible smartphone (iOS or Android) with cellular or Wi-Fi access and is willing to use study applications. * Able to read, understand, and provide informed consent in English. * Willing and able to attend required in-person study visits. Exclusion Criteria: Participants will be excluded if they meet any of the following criteria: * Plans to discontinue GLP-1RA therapy or substantially modify treatment during the 12-week study period. * Self-reported musculoskeletal injury, orthopedic limitation, or surgery within the previous 6 months that would contraindicate resistance training participation. * Self-reported unstable cardiovascular disease or cardiac event within the previous 6 months. * Currently pregnant or planning to become pregnant during the study period. * Active eating disorder or psychiatric condition that may interfere with study participation. * Unable to use smartphone applications required for the intervention. * Current participation in another pharmacological, behavioral, weight management, or chronic disease management program that could confound study outcomes.