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The Effect of Sea Buckthorn Extract in Patients With Type 1 Diabetes
Sponsor: The First Affiliated Hospital of Guangzhou Medical University
Summary
Type 1 diabetes (T1D) is an autoimmune disease characterized by the destruction of insulin-producing β-cells by autoreactive T cells. Sea buckthorn (SBT), a traditional Chinese medicine homologous to food, confers beneficial effects on the autoimmune system. Whether SBT regulates the glucose metabolism and immune microenvironment in T1D remains unknown. This study aims to investigate the impact of SBT on glycemic control and T-cell balance in patients with T1D. Patients with T1D consumed 10g of SBT extracts daily for 12 weeks. Clinical and experimental data were analyzed at the baseline and after 12 weeks of SBT treatment. Healthy controls were enrolled with no treatment. Side adverse effects will be recorded in this study.
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2020-01-01
Completion Date
2023-12-31
Last Updated
2026-08-26
Healthy Volunteers
Yes
Conditions
Interventions
Sea buckthorn
Sea buckthorn extract One of the differences between these two studies and ours is that the SBT used in our study is extracted by supercritical extraction technology without additional components.
Locations (1)
The first affiliated hospital of guangzhou medical University
Guangzhou, Guangdong, China