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Differential Clinical Phenotypes Of Early CD4+ And CD8+ T-Cell Recovery And Association With 28-Day Mortality In Sepsis Patients
Sponsor: Sichuan Provincial People's Hospital
Summary
This is a retrospective non-interventional cohort study. Medical records of adult patients with sepsis admitted to the intensive care unit will be retrospectively reviewed. We aim to compare clinical manifestations, laboratory indicators and prognosis among different sepsis phenotypes, so as to provide clinical reference for early identification and risk stratification of sepsis. No intervention will be performed on patients in this study.
Official title: Differential Clinical Phenotypes Of Early CD4+ And CD8+ T-Cell Dynamic Recovery And Their Association With 28-Day All-Cause Mortality Among Sepsis Patients
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
303
Start Date
2022-01-01
Completion Date
2025-04-01
Last Updated
2026-08-26
Healthy Volunteers
No
Conditions
Interventions
CD4+/CD8+ T-cell dynamic recovery status
Dynamic recovery status of CD4⁺ and CD8⁺ T-lymphocyte subsets based on two sequential lymphocyte count measurements in sepsis patients, retrospective chart review, no investigator-initiated intervention.
Locations (1)
Sichuan Provincial People's Hospital, Intensive Care Unit
Chengdu, Sichuan, China