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Scaffolding in AI-Empowered Cognitive Training Improves Outcomes in Cognitive Impairment
Sponsor: Xuanwu Hospital, Beijing
Summary
This retrospective study aimed to validate and compare two individualized, closed-loop, AI-driven computerized cognitive training programs with a conventional non-AI training program in a real-world clinical setting. Using objective tablet-recorded data from patients' prior treatment, participants were categorized into three groups according to the training recommendation strategy they actually received. Changes in global cognitive function and specific cognitive domains after 8 weeks of training were compared across groups to evaluate the association between different training strategies and cognitive outcomes.
Official title: Scaffolding in AI-Empowered Cognitive Training Improves Outcomes in Cognitive Impairment: A Real-world Retrospective Cohort Study
Key Details
Gender
All
Age Range
45 Years - Any
Study Type
OBSERVATIONAL
Enrollment
516
Start Date
2026-08-15
Completion Date
2027-08-25
Last Updated
2026-08-26
Healthy Volunteers
No
Conditions
Interventions
AI-Based Adaptive CCT Optimized for Cognitive Improvement
Participants received a multi-domain computerized cognitive training program delivered on a tablet. The program used an AI-based adaptive, closed-loop recommendation strategy to individualize training tasks and difficulty levels, with the goal of maximizing cognitive improvement over the training period.
AI-Based Adaptive CCT Optimized for Cognitive Performance
Participants received a multi-domain computerized cognitive training program delivered on a tablet. The program used an AI-based adaptive, closed-loop recommendation strategy to individualize training tasks and difficulty levels, with the goal of maximizing cognitive task performance during training.
Conventional Non-AI CCT
Participants received a conventional computerized cognitive training program delivered on a tablet. Training tasks were randomly selected within the cognitive domains corresponding to participants' symptomatic impairments and difficulty levels were fixed.
Locations (1)
Xuanwu Hospital, Capital Medical University
Beijing, China