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COMPLETED
NCT07790003

Dietary Fibre Supplementation to Delay Disease Progression in Early Prostate Cancer

Sponsor: University of Aberdeen

View on ClinicalTrials.gov

Summary

This qualitative research study, based on semi-structured interviews and a focus group, aims to explore the attitudes of prostate cancer patients on active surveillance (AS) towards dietary fibre supplementation, given the potential benefits demonstrated in previous research. Prostate cancer patients on AS, often overlooked in the literature, experience cyclical anxiety, particularly regarding disease progression. Lifestyle modifications, including dietary changes, are pursued by a number of these patients as a preventative measure. Dietary fibre such as inulin and psyllium have promising results in studies of pelvic cancers. However, it is important to note that these findings do not directly apply to patients who are currently undergoing AS for prostate cancer. Despite potential side effects, these dietary fibres may contribute to anti-inflammatory and antitumorigenic effects. Building on this evidence, we aim to explore patient perspectives on the feasibility and acceptability of dietary fibre supplementation during AS. The insights gained will guide the development of a feasibility and/or pilot studies and, subsequently, a multicentre randomised controlled trial. If successful, this intervention could potentially reshape clinical practice for patients with prostate cancer on AS.

Key Details

Gender

MALE

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

10

Start Date

2024-07-03

Completion Date

2024-10-22

Last Updated

2026-08-27

Healthy Volunteers

Not specified

Interventions

OTHER

Qualitative semi-structured interviews

The research fellow will conduct a total of 12 semi-structured individual interviews, either via video (MS Teams) or telephone format, based on participant preference. We will employ a semi-structured interview methodology as it collects richer data and allows for in-depth exploration of the participant's insights. Interviews will be conducted at a time convenient to the participant. The topic guide will structure the interview format. Each participant will be interviewed only once.

OTHER

Focus group

Subsequently, we will hold one focus group online via video (MS Teams) with six participants, which will be run by the research fellow and one of the academic supervisors. The topic guide will structure the interview format.

Locations (1)

NHS Grampian - Aberdeen Royal Infirmary

Aberdeen, Aberdeen City, United Kingdom