Clinical Research Directory
Browse clinical research sites, groups, and studies.
Photobiomodulation on NMES-Induced Muscle Fatigue and Damage
Sponsor: Federal University of Rio Grande do Sul
Summary
Neuromuscular electrical stimulation (NMES) is effective for strength training and rehabilitation, but non-selective motor unit recruitment often induces rapid fatigue, discomfort, and muscle damage. Photobiomodulation therapy (PBMT) has been proposed to attenuate muscle fatigue and accelerate recovery, yet evidence regarding its acute prophylactic effects against NMES-induced fatigue remains limited. This randomized, single-blind, sham-controlled crossover pilot trial evaluates the acute effects of pre-exercise PBMT on knee extensor neuromuscular fatigability, muscle damage, discomfort, and functional recovery following a standardized NMES fatigue protocol in healthy adults.
Official title: Effects of Photobiomodulation and Stimulation Sites on Muscle Fatigue and Damage Induced by Neuromuscular Electrical Stimulation in Healthy Individuals
Key Details
Gender
All
Age Range
18 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
12
Start Date
2022-11-01
Completion Date
2023-12-01
Last Updated
2026-08-31
Healthy Volunteers
Yes
Conditions
Interventions
Photobiomodulation Therapy (PBMT)
Multi-diode cluster probe (GaAlAs laser; 5 diodes; wavelength: 810 nm; power output: 200 mW per diode; continuous mode) applied across 8 points over the quadriceps femoris (3 on rectus femoris, 3 on vastus lateralis, and 2 on vastus medialis) for 30 seconds per point (30 J/point), delivering a total energy dose of 240 J per limb.
Sham Photobiomodulation
Identical probe positioning over the 8 quadriceps locations for 30 seconds per point with the laser device completely turned off. Auditory headphones are used to blind participants against sound cues.
Locations (1)
Laboratório de Pesquisa do Exercício
Porto Alegre, Rio Grande do Sul, Brazil