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Improvement of Total Knee Arthroplasty Effectiveness Using Preoperative Prehabilitation
Sponsor: Samara State Medical University
Summary
Total knee arthroplasty (TKA) is the most effective treatment for stage III-IV knee osteoarthritis (OA). However, up to 30% of patients remain dissatisfied due to periarticular functional insufficiency, pain, and movement limitations. This study aims to improve TKA outcomes by developing and implementing a multimodal prehabilitation approach based on OA phenotypes (chronic pain, inflammatory, biomechanical) to correct clinical and functional disorders preoperatively, thereby enhancing postoperative recovery and quality of life.
Official title: Improvement of Total Knee Arthroplasty Effectiveness Through Preoperative Correction of Clinical and Functional Disorders Using a Multimodal Phenotype-Based Prehabilitation Approach
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
64
Start Date
2023-01-01
Completion Date
2025-12-31
Last Updated
2026-08-27
Healthy Volunteers
No
Interventions
Multimodal phenotype-based prehabilitation
A 4-week preoperative program including active/passive mechanotherapy, breathing exercises, psychological support, and phenotype-specific interventions (SMT for chronic pain, magnetotherapy for inflammation, robotic mechanotherapy for biomechanical restrictions) combined with kinesiotaping, aimed at correcting clinical and functional disorders before TKA.
Locations (1)
Clinics of Samara State Medical University, Department of Traumatology and Orthopedics
Samara, Samara Oblast, Russia