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Combination of High-flow Nasal Oxygen (Optiflow) and Vibrating Membrane Nebuliser (Aerogen) in the Pre-hospital Setting - Before/After Study
Sponsor: Centre Hospitalier Sud Francilien
Summary
The aim of this observational before/after study is to determine how to optimally administer oxygen to patients experiencing an asthma or COPD exacerbation in emergency medical services. The aim will be to determine which method will achieve the target oxygen saturation objectives: \> 95% in asthma exacerbations and between 88% and 92% (or \> 92% in ambient air or with FiO2 21%) in COPD exacerbations. The study will compare a group "before" receiving standard care with a nebulizer mask to a group "after" using a combination of a vibrating membrane nebulizer and high-flow nasal oxygen.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
0
Start Date
2026-10-01
Completion Date
2027-10-01
Last Updated
2026-08-28
Healthy Volunteers
No
Interventions
Vibrating membrane nebulizer and high-intensity nasal oxygen
Vibrating membrane nebulizer and high-intensity nasal oxygen
nebulizer mask and oxygen therapy of 6 to 9 liters per minute
nebulizer mask and oxygen therapy of 6 to 9 liters per minute
Locations (1)
Centre Hospitalier Sud Francilien
Corbeil-Essonnes, France