Clinical Research Directory

Inclusion for donor: * Donor age \> 18 years * Brain Death (DBD) or Circulatory Death \< 50 years (DCD\<50) * Accepted for transplantation according to local criteria Inclusion for recipient: * Male or female, age \> 18 years * Able and willing to comply with all study requirements (in opinion of investigator or deputy) * General inclusion criteria applicable to kidney transplantation: * Listed for renal transplantation due to end stage renal disease on the Eurotransplant (ET) list * Fit to proceed with kidney transplantation (in opinion of investigator or deputy) Exclusion for donor: * Donor kidneys accepted as a pair for dual transplant * Circulatory Death ≥ 50 years (DCD 50+) * Participation in an investigational study likely to affect interpretation of the trial data Exclusion for recipient: * General exclusion criteria applicable to kidney transplantation * Breast-feeding or pregnant, as confirmed by pregnancy test or blood test, or plans to become pregnant over the study period * Participation in an investigational study likely to affect interpretation of the trial data * Mental disabilities that may affect the understanding of the study requirements including the ability to adhere to medication regime (in opinion of investigator or deputy) * Undergoing living donor kidney transplantation * Undergoing dual kidney transplantation * Undergoing transplantation of other organ(s) in addition to the kidney * Highly immunized patients with vPRA \> 85% (as confirmed by routine cross-matching test) * Other substantial risk of transplant not proceeding (in opinion of investigator or deputy) * Other significant disease or disorder which, in the opinion of the Investigator, may: (i) put the participant at risk by participating in the study; (ii) influence the result of the study; (iii) affect the participant's ability to participate in the study