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NOT YET RECRUITING
NCT07792408
PHASE1

Effects of VX-407 on the Pharmacokinetics of Combined Oral Contraceptives

Sponsor: Vertex Pharmaceuticals Incorporated

View on ClinicalTrials.gov

Summary

The purpose of the study is to evaluate the pharmacokinetic effects and safety and tolerability of VX-407 when coadministered with oral contraceptives.

Official title: A Phase 1, Open-label Drug Interaction Study to Evaluate the Effect of VX-407 on the Pharmacokinetics of Combined Oral Contraceptives

Key Details

Gender

FEMALE

Age Range

18 Years - 50 Years

Study Type

INTERVENTIONAL

Enrollment

148

Start Date

2026-08-28

Completion Date

2027-03-20

Last Updated

2026-08-28

Healthy Volunteers

Yes

Interventions

DRUG

VX-407

Tablets for Oral Administration.

DRUG

LNG/EE

Combination Tablets for Oral Administration.

DRUG

NGM/EE

Combination Tablets for Oral Administration.

DRUG

NET/EE

Combination Tablets for Oral Administration.

DRUG

DRSP/EE

Combination Tablets for Oral Administration.