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Increasing Mitochondrial Respiration as a Novel Mechanism for Cognitive Augmentation
Sponsor: Francisco Gonzalez-Lima, PhD
Summary
The purpose of this study is to investigate the effects of increasing brain energy on cognition. The hypothesis is that by using a special kind of light, in combination with a nutritional supplement, it may be possible to increase energy production in the brain, which may lead to improvements in cognition.
Key Details
Gender
All
Age Range
18 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
180
Start Date
2026-10-01
Completion Date
2030-05
Last Updated
2026-08-28
Healthy Volunteers
Yes
Conditions
Interventions
Active transcranial photobiomodulation
Infrared light delivered to the forehead, administered with a headset using light-emitting diodes (LEDs)
Active MCT dietary supplementation
Commercially-available food-grade refined coconut oil for ketogenic dietary supplementation
Sham photobiomodulation
Identical procedure as active group, but with 5% of light emitted by the device.
Sham dietary supplementation
Identical appearance and administration as active dietary supplementation, but with commercially-available food-grade sunflower oil (comparable caloric value without ketone production).
Locations (1)
The University of Texas at Austin
Austin, Texas, United States