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Intravenous Magnesium Sulphate Versus Lignocaine for Attenuating Hemodynamic Responses to Laryngoscopy and Endotracheal Intubation
Sponsor: Lady Reading Hospital, Pakistan
Summary
This study will compare intravenous magnesium sulfate with intravenous lidocaine for reducing the cardiovascular response to endotracheal intubation in adult patients undergoing general anesthesia. Eligible participants will receive either magnesium sulfate or lidocaine before endotracheal intubation. Heart rate and blood pressure will be recorded at predefined time points before and after intubation to compare the effectiveness of the two interventions in attenuating the hemodynamic response to laryngoscopy and endotracheal intubation.
Official title: Comparison of Intravenous Magnesium Sulphate and Lignocaine in Attenuation of Hemodynamic Responses to Laryngoscopy and Endotracheal Intubation
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
78
Start Date
2026-08-20
Completion Date
2026-09-20
Last Updated
2026-09-08
Healthy Volunteers
Yes
Interventions
Magnesium Sulphate infusion
intravenous magnesium Sulphate 30mg /kg diluted in 100ml normal saline, administered 90 sec before induction of general anesthesia