Clinical Research Directory

Inclusion Criteria: * History of ≥2 consecutive unexplained miscarriages before 20 weeks of gestation. * Confirmed intrauterine pregnancy by ultrasound and/or serum β-hCG (≥5 weeks). * Willingness to follow study procedures (progesterone use, possible daily - injections) and provide written informed consent. * No medical contraindication to progesterone or LMWH. Exclusion Criteria: * Documented antiphospholipid syndrome or any current anticoagulant requirement. * Anatomical abnormalities (e.g., significant uterine malformations, large fibroids) conclusively linked to RPL. * Known hypersensitivity to enoxaparine or heparins, or prior heparin-induced thrombocytopenia (HIT). * Use of systemic steroids (beyond standard pregnancy doses) for other immunological or inflammatory conditions. * Severe renal insufficiency (eGFR \<30 mL/min), advanced liver disease, or other clinically significant systemic autoimmune disease (e.g., systemic lupus erythematosus, rheumatoid arthritis) that may affect pregnancy or study compliance. * Inability or unwillingness to comply with study requirements (language barriers, severe psychiatric conditions, etc.). * Abnormal karyotype