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Characterisation of MNEsic Involvement in Patients With Obesity.
Sponsor: University Hospital, Bordeaux
Summary
The aim of the study is therefore to characterise memory impairment in a middle-aged population with obesity and to clarify the role of inflammation in obesity-related memory impairment. The hypothesise that, as in an elderly population, neurological and memory impairment in a population of middle-aged obese individuals is heterogeneous, with varying levels of memory impairment characterised by neuropsychological test results. This heterogeneity in neuropsychological tests may be linked to markers of inflammation and brain imaging biomarkers identified previously in the litterature.
Key Details
Gender
All
Age Range
30 Years - 50 Years
Study Type
OBSERVATIONAL
Enrollment
150
Start Date
2027-01
Completion Date
2030-02
Last Updated
2026-09-01
Healthy Volunteers
No
Conditions
Interventions
RMI and Questionnaires
Magnetic resonance imaging (MRI) will collect anatomical information (3D T1 weighted images) to compute the volumes of the hypothalamus, hippocampus and the other brain parcels. Executive functions using the CANTAB tests and validated questionnaires will be performed.