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VO2max and Substrate Crossover Point
Sponsor: Celil Kaçoğlu
Summary
This study aims to investigate the relationship between maximal oxygen uptake (VO2max) and the substrate crossover point during incremental exercise. A total of 20 physical education students are recruited to complete a maximal incremental treadmill test using the standard Bruce protocol. Indirect calorimetry is utilized to assess oxygen uptake (VO2), carbon dioxide production (VCO2), and energy substrate utilization patterns. The substrate crossover point is operationally defined at a respiratory exchange ratio (RER) threshold of 0.85, indicating the metabolic transition toward predominant carbohydrate oxidation. The primary objective is to evaluate how variations in aerobic capacity influence the timing, oxygen uptake, and heart rate (HR) responses at this metabolic transition threshold.
Official title: Higher VO2max Delays Substrate Switching and Shifts the Crossover Point to Greater Oxygen Uptake During Incremental Exerciseebys
Key Details
Gender
All
Age Range
18 Years - 30 Years
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2026-05-01
Completion Date
2026-07-15
Last Updated
2026-09-02
Healthy Volunteers
Yes
Conditions
Interventions
Incremental Graded Exercise Test (Bruce Protocol)
Participants perform a maximal treadmill exercise test following the standardized Bruce Protocol. The test begins with a warm-up, followed by progressive 3-minute stages with continuous increases in speed and incline until voluntary exhaustion. Indirect calorimetry is used continuously via breath-by-breath gas analysis to measure VO2VCO2, and RER for substrate crossover determination.
Locations (1)
Eskişehir Technical University
Eskişehir, Tepebaşi, Turkey (Türkiye)