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Investigation of the Association of Multimodal Neuroimaging and Peripheral Biomarkers With Executive Functions and Emotional Regulation in Adolescents With Attention-Deficit/Hyperactivity Disorder
Sponsor: Akdeniz University
Summary
The purpose of this observational study is to investigate the relationships among resting-state brain connectivity, peripheral blood biomarkers, executive functions, and emotional regulation in adolescents with attention-deficit/hyperactivity disorder (ADHD). The study will include 40 adolescents aged 10 to 18 years with ADHD and 40 age- and sex-matched healthy controls. Participants will undergo clinical and psychological assessments, resting-state functional magnetic resonance imaging, and blood sampling. Serum levels of BDNF, cortisol, IL-1α, IFN-γ, TNF-α, and IL-6 will be measured. The study will examine whether differences in brain connectivity and biomarker levels are associated with executive functioning and emotional regulation.
Key Details
Gender
All
Age Range
10 Years - 18 Years
Study Type
OBSERVATIONAL
Enrollment
80
Start Date
2026-03-01
Completion Date
2027-01-31
Last Updated
2026-09-02
Healthy Volunteers
Yes
Interventions
No Intervention
This is an observational study. No intervention or treatment is assigned to participants. Participants are assessed using clinical and neuropsychological assessments, resting-state functional magnetic resonance imaging, and peripheral blood biomarker measurements.
Locations (1)
Akdeniz University Faculty of Medicine Hospital
Antalya, Turkey (Türkiye)