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ACTIVE NOT RECRUITING
NCT07800767

Anesthesia Management, Inflammatory Response and Recovery After Non-intubated VATS Pericardial Window

Sponsor: Koşuyolu Kartal Heart Training and Research Hospital

View on ClinicalTrials.gov

Summary

Non-intubated video-assisted thoracoscopic surgery (NIVATS) is performed under spontaneous ventilation and avoids tracheal intubation and one-lung mechanical ventilation. It is increasingly used for the surgical management of pericardial effusion, where a pericardial window is created thoracoscopically. Because NIVATS avoids airway instrumentation and positive-pressure ventilation, it has been proposed to blunt the perioperative inflammatory and stress response and to support enhanced recovery after surgery targets. Within NIVATS, anaesthetic management is not uniform. In routine institutional practice, some patients are managed with procedural sedation plus systemic opioid analgesia, while others receive procedural sedation plus a thoracic regional analgesia technique. Whether this difference in analgesic strategy translates into a measurable difference in the systemic inflammatory response or in early recovery outcomes has not been established. This single-centre retrospective cohort study will review the records of adult patients who underwent NIVATS pericardial window creation for pericardial effusion at a tertiary hospital.

Official title: Effect of Different Anesthesia Management Approaches on Inflammatory Response and Enhanced Postoperative Recovery Outcomes in Non Intubated Video-assisted Thoracoscopic Surgery: A Single-centre Retrospective Cohort Study

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

OBSERVATIONAL

Enrollment

120

Start Date

2026-08-30

Completion Date

2026-12-30

Last Updated

2026-09-02

Healthy Volunteers

No

Interventions

OTHER

Systemic opioid-based analgesia during NIVATS

Procedural sedation with systemic opioid analgesia, administered as part of routine clinical care. No intervention was assigned by the investigators.

PROCEDURE

Thoracic regional analgesia during NIVATS

Procedural sedation combined with paravertebral block, erector spinae plane block, or serratus anterior/intercostal plane block, administered as part of routine clinical care. No intervention was assigned by the investigators.

Locations (1)

Kosuyolu Heart Training and Research Hospital

Istanbul, Kartal, Turkey (Türkiye)