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Comparing Two Low-Carbohydrate Diets With a Standard Diet in Type 2 Diabetes
Sponsor: National Nutrition and Food Technology Institute
Summary
Type 2 diabetes is often accompanied by high blood triglycerides and excess weight, and diet plays a central role in managing these conditions together. The purpose of this study is to compare the effects of two moderate low-carbohydrate diets - one higher in protein and one higher in fat - against a standard diet, on blood sugar control, blood lipids (especially triglycerides), body weight, and blood pressure in adults with type 2 diabetes, hypertriglyceridemia, and overweight or obesity.
Official title: Comparison of Two Moderate Low-Carbohydrate Diets (High-Protein and High-Fat) Versus a Standard Diet on Metabolic Indices in Patients With Type 2 Diabetes, Hypertriglyceridemia, and Overweight or Obesity: A Three-Arm Randomized Clinical Trial
Key Details
Gender
All
Age Range
30 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
168
Start Date
2026-09-20
Completion Date
2026-09-20
Last Updated
2026-09-03
Healthy Volunteers
No
Interventions
High-Protein Low-Carbohydrate Diet
A calorie-restricted (500 kcal/day below baseline needs) diet providing 40% of energy from complex carbohydrates, 30% from fat (20% unsaturated with a 4:1 MUFA/PUFA ratio, 10% saturated), and 30% from protein (15% plant-based), delivered over 12 weeks as 5 individualized daily meals.
High-Fat Low-Carbohydrate Diet
A calorie-restricted (500 kcal/day below baseline needs) diet providing 40% of energy from complex carbohydrates, 45% from fat (35% unsaturated with a 4:1 MUFA/PUFA ratio, 10% saturated), and 15% from protein, delivered over 12 weeks as 5 individualized daily meals.
Standard diet
A calorie-restricted (500 kcal/day below baseline needs) standard diet providing 55% of energy from complex carbohydrates, 30% from fat (20% unsaturated with a 4:1 MUFA/PUFA ratio, 10% saturated), and 15% from protein, delivered over 12 weeks as 5 individualized daily meals.