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To Evaluate If Preoperative 7 Days Low Calorie Diet Reduces Postoperative Morbidity in Liver Surgery
Sponsor: Region Skane
Summary
The rationale for this study is to evaluate whether a standardized, preoperative, short-term Low Calorie Diet (LCD) reduces intraoperative bleeding and postoperative morbidity in liver surgery. Participants with a BMI of 30 or higher, scheduled for liver surgery, if accepting participation, will be randomized to a 7 day LCD or no intervention. A previous small single center RCT have shown significantly reduced intraoperative blood loss and a tendency towards less postoperative complications. This multi-centre study aims to include enough patients with power to analyze also postoperative complications.
Official title: Low Calorie Diet Before Liver Surgery - A Nordic Multicentre Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2026-06-01
Completion Date
2029-07-01
Last Updated
2026-09-03
Healthy Volunteers
No
Conditions
Interventions
Low calorie meal replacement plan
Short-term LCD one week prio to liver surgery for patients with a BMI 30 or higher
Locations (1)
Department och Surgery, Skane University Hospital
Lund, Sweden