Clinical Research Directory

Inclusion Criteria: * Healthy volunteers, 18-75 years of age. * Informed consent signed by participant according to the guidelines of the institutional review board. * Female participants of childbearing age must not be lactating due to theoretical potential harm to the infant from exposure to radiation. Exclusion Criteria: * Participant has been treated for cancer. * Participant has experienced a stroke. * Participant has history of seizures. * Participant has been diagnosed with a neurodegenerative or neurodevelopmental disorder. * Participant has been diagnosed with a psychiatric disorder such as bipolar or schizophrenia. * Participant has been diagnosed or is suspected to have had a traumatic brain injury or concussion (TBI) within the last year. * Participant has known disease of the lung, liver, kidneys, gastrointestinal tract, bones/joints, or known immune suppression or autoimmune disease likely to have active inflammation (examples to exclude: Crohn's disease, COPD, asthma) * Participant has prosthetic or indwelling device(s), including IUD, currently, or has had one in the past 60 days. * Participant has undergone any procedure of an internal organ. * Participant is pregnant or breastfeeding. * Estimated glomerular filtration rate \< 45 ml/minute/1.73m2 * Participants actively taking anti-inflammatory medication or have a condition requiring them to take anti-inflammatory medication (e.g. NSAIDs or steroids). * Participant has any condition that would, in the opinion of the investigator, place the subject at an unacceptable risk of injury or render the subject unable to meet the requirements of the protocol, including being unable to tolerate the PET scan procedures. * Inability or unwillingness of research participant or legal guardian/representative to give written informed consent.