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NOT YET RECRUITING
NCT07802457

Diagnosis of Women With ANOCA

Sponsor: NHS Greater Glasgow and Clyde

View on ClinicalTrials.gov

Summary

Angina is a feeling of chest pain or discomfort which can happen if there is reduced blood flow to the heart. Patients can experience angina with no obstructive coronary arteries (ANOCA) which is a difficult condition to treat (ie relieve angina) since few randomised, controlled therapy trials have been undertaken for ANOCA. Until now, angina has been mainly studied in men even though women are at least two-fold more likely than men to experience ANOCA. Research studies involving people with ANOCA may have limitations in relation to retrospective collection of historical data or lack of prospectively collected contemporary data. These limitations are particularly relevant to women with ANOCA which is an area that has been historically under-recognised. Prior studies may have data gaps, such as for women's health. For these reasons, the Investigators propose a research registry for women with ANOCA which aims to plug these gaps. The Investigators aim to understand the biological mechanisms behind angina in women specifically. This study will categorise ANOCA into different subtypes and offer women the opportunity to take part in research studies to treat ANOCA. The Investigators will also follow the women's health over time through remote data collection methods.

Official title: Diagnosis of Women With ANOCA: a Registry-based Cohort Study

Key Details

Gender

FEMALE

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

400

Start Date

2026-11-27

Completion Date

2029-06-30

Last Updated

2026-09-03

Healthy Volunteers

No

Locations (11)

Essex cardiothoracic centre

Basildon, United Kingdom

Royal United Hospital Bath

Bath, United Kingdom

Royal Papworth Hospital

Cambridge, United Kingdom

Queen Elizabeth University Hospital Clinical Research Facility,

Glasgow, United Kingdom

Leeds General Infirmary

Leeds, United Kingdom

Brompton Hospital

London, United Kingdom

Guys and St Thomas Hospital

London, United Kingdom

Kings college london

London, United Kingdom

Freeman Hospital

Newcastle upon Tyne, United Kingdom

Nottingham City Hospital

Nottingham, United Kingdom

Sunderland Royal Hospital

Sunderland, United Kingdom