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Diagnosis of Women With ANOCA
Sponsor: NHS Greater Glasgow and Clyde
Summary
Angina is a feeling of chest pain or discomfort which can happen if there is reduced blood flow to the heart. Patients can experience angina with no obstructive coronary arteries (ANOCA) which is a difficult condition to treat (ie relieve angina) since few randomised, controlled therapy trials have been undertaken for ANOCA. Until now, angina has been mainly studied in men even though women are at least two-fold more likely than men to experience ANOCA. Research studies involving people with ANOCA may have limitations in relation to retrospective collection of historical data or lack of prospectively collected contemporary data. These limitations are particularly relevant to women with ANOCA which is an area that has been historically under-recognised. Prior studies may have data gaps, such as for women's health. For these reasons, the Investigators propose a research registry for women with ANOCA which aims to plug these gaps. The Investigators aim to understand the biological mechanisms behind angina in women specifically. This study will categorise ANOCA into different subtypes and offer women the opportunity to take part in research studies to treat ANOCA. The Investigators will also follow the women's health over time through remote data collection methods.
Official title: Diagnosis of Women With ANOCA: a Registry-based Cohort Study
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
400
Start Date
2026-11-27
Completion Date
2029-06-30
Last Updated
2026-09-03
Healthy Volunteers
No
Locations (11)
Essex cardiothoracic centre
Basildon, United Kingdom
Royal United Hospital Bath
Bath, United Kingdom
Royal Papworth Hospital
Cambridge, United Kingdom
Queen Elizabeth University Hospital Clinical Research Facility,
Glasgow, United Kingdom
Leeds General Infirmary
Leeds, United Kingdom
Brompton Hospital
London, United Kingdom
Guys and St Thomas Hospital
London, United Kingdom
Kings college london
London, United Kingdom
Freeman Hospital
Newcastle upon Tyne, United Kingdom
Nottingham City Hospital
Nottingham, United Kingdom
Sunderland Royal Hospital
Sunderland, United Kingdom