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PENG Block Versus Intrathecal Morphine for Early Postoperative Recovery After Total Hip Arthroplasty
Sponsor: Erzincan Binali Yildirim Universitesi
Summary
The goal of this clinical trial is to compare the PENG block with intrathecal morphine for early postoperative recovery and pain control in adults undergoing elective total hip arthroplasty. The main question it aims to answer is: Is there a difference between PENG block and intrathecal morphine in quality of recovery 24 hours after surgery, as measured by the Quality of Recovery-15 (QoR-15) questionnaire? Researchers will also compare postoperative pain, opioid use, mobilization, motor function, and treatment-related side effects between the two groups. Participants will be randomly assigned to receive either a PENG block or intrathecal morphine in addition to spinal anesthesia and standard multimodal pain treatment. Participants will complete the QoR-15 questionnaire before surgery and 24 hours after surgery. Pain scores, opioid use, mobilization, motor function, and side effects will be assessed during the first 24 hours after surgery.
Official title: Comparison of PENG Block and Intrathecal Morphine in Terms of Early Postoperative Quality of Recovery and Analgesic Efficacy in Patients Undergoing Elective Total Hip Arthroplasty: A Prospective Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
90
Start Date
2026-09-01
Completion Date
2027-09-01
Last Updated
2026-09-03
Healthy Volunteers
No
Conditions
Interventions
Pericapsular nerve group (PENG) block
Participants will receive an ultrasound-guided pericapsular nerve group (PENG) block after spinal anesthesia. The total injectate volume will be 20 mL, with an intended dose of 100 mg bupivacaine (20 mL of 0.5% bupivacaine). The bupivacaine dose will be reduced when necessary to ensure that the total bupivacaine dose, including the dose administered for spinal anesthesia, does not exceed 2 mg/kg. When dose reduction is required, 0.9% saline will be added to maintain a total injectate volume of 20 mL.
Intrathecal Morphine
100 micrograms of preservative-free morphine administered intrathecally during spinal anesthesia
Locations (1)
Erzincan Binali Yildirim University Mengucek Gazi Training and Research Hospital
Erzincan, Erzincan, Turkey (Türkiye)