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Frailty, Immunonutrition, Surgery Type, and Biologic Recovery in Elderly Gastric Cancer
Sponsor: Kocaeli City Hospital
Summary
This prospective observational cohort study will evaluate the effects of multidimensional frailty phenotypes, immunonutritional status, and surgical approach on biological recovery in patients aged 60 years and older undergoing surgery for gastric cancer. Preoperative assessment will include physical and cognitive frailty, nutritional status, handgrip strength, and skeletal muscle characteristics on computed tomography. Patients will be followed prospectively during the perioperative period, including assessment of inflammatory markers, postoperative complications, delirium, hospital length of stay, and functional recovery. The study aims to determine whether multidimensional frailty and immunonutritional factors are associated with postoperative outcomes and whether surgical approach influences biological recovery in older patients with gastric cancer. A total of 328 patients are planned to be included at Kocaeli City Hospital.
Official title: The Effects of Multidimensional Frailty Phenotypes, Immunonutritional Status, and Surgical Approach on Biological Recovery in Elderly Patients Undergoing Gastric Cancer Surgery: A Prospective Observational Study
Key Details
Gender
All
Age Range
60 Years - Any
Study Type
OBSERVATIONAL
Enrollment
328
Start Date
2026-09
Completion Date
2028-08
Last Updated
2026-09-03
Healthy Volunteers
No
Conditions
Interventions
Laparoscopic Gastrectomy
Elective radical gastrectomy performed using a laparoscopic approach as part of routine clinical care. The surgical approach is not assigned by the study
Open Gastrectomy
Elective radical gastrectomy performed using an open approach as part of routine clinical care. The surgical approach is not assigned by the study
Locations (1)
Kocaeli City Hospital
Kocaeli, İZMİT, Turkey (Türkiye)