Clinical Research Directory

Inclusion Criteria: * Chronic stroke, more than 6 months post-stroke * Clinical evidence of hemiparetic gait * Ankle dorsiflexion and plantarflexion strength on the affected side graded 1/5 (trace contraction) to 4/5 (reduced strength) on manual muscle testing * Able to independently complete the 10-Meter Walk Test at a walking speed less than 1.0 m/s, with or without an assistive device Exclusion Criteria: * Self-reported unstable angina, myocardial infarction within the past 3 months, congestive heart failure (NYHA Class II), or hemodynamically significant valvular disease * Self-reported hypertension that is a contraindication to routine physical therapy (greater than 160/100 mmHg on two assessments) * Self-reported hospitalization within the past 3 months for severe medical illness * Self-reported symptomatic peripheral arterial occlusive disease * Self-reported orthopedic conditions or chronic pain that significantly alter gait function * Self-reported pulmonary or renal failure * Self-reported active cancer * Self-reported history of a non-stroke neuromuscular disorder restricting gait * Aphasia or cognitive functioning that confounds participation, defined as unable to follow two-step commands or by judgment of the evaluating therapist * Self-reported history of cerebellar stroke or observable cerebellar signs * Self-reported botulinum toxin prescribed for the lower extremities within the previous 3 months