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Assessment of Lung Function (Lufu) at Sea Level LA vs. High Altitude HA in Healthy Individuals
Sponsor: Silvia Ulrich Somaini
Summary
To study the effect of a re-ascent to high altitude (Quito Ecuador: 2850m) after a one-week stay at sea level (after prior descent from 2850m) on lung function and pulmonary resistance/reactance in healthy individuals, who live permanently \> 2600m.
Official title: Effect of a One-week Descent From 2850m to Sea Level and Re-ascent in Patients With Pulmonary Arterial Hypertension and Healthy Controls Permanently Living > 2600m on Pulmonary Hemodynamics, Exercise Capacity, Blood Oxygenation, Sleep Disordered Breathing and Further Outcomes
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
14
Start Date
2026-09-25
Completion Date
2026-12-31
Last Updated
2026-09-04
Healthy Volunteers
Yes
Conditions
Interventions
Re-ascent from sea level to 2850m
Descent from 2850m to sea level with a stay for 7 days and re-ascent/return back to their usual living altitude at 2850m
Locations (1)
University Hospital of Zurich
Zurich, Switzerland