Clinical Research Directory

Inclusion Criteria: * Children and adolescents aged 10-18 years. * Newly diagnosed type 1 diabetes mellitus (within 6 weeks of diagnosis, defined as the day of starting insulin therapy). * Presence of at least two positive islet autoantibody (anti glutamic acid decarboxylase antibodies, anti- tyrosine phosphataseantibodies ,anti- zinc transporter 8 protein antibodies , or anti-insulin antibodies). * Ability to comply with study procedures. Exclusion Criteria: * Previous diagnosis of other endocrine disorders or autoimmune disorder (e.g. autoimmune thyroiditis). * Current or planned use of medications that might affect glucose metabolism (e.g., corticosteroids, immunomodulators). * Known allergy or intolerance to verapamil. * Cardiac conduction abnormalities, heart block, or significant cardiac disease. * Systolic or diastolic blood pressure \< 5th percentile for age and gender. * Severe hepatic or renal impairment. * Participation in another interventional clinical trial. * Inability to follow the protocol for any reason as determined by the investigator. * Elevated liver enzymes \>1.5 × upper limit of normal at screening