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Broadband Near Infrared Spectroscopy to Understand the Role of Brain Cytochrome C Oxidase in Bipolar Disorder
Sponsor: Martin Lan
Summary
People with a diagnosis of bipolar disorder who are depressed will have a light-based imaging of the brain (Near Infrared Spectroscopy) before and after they have treatment for their depression with a standard, approved medication named lurasidone. They will also answer questions about their history, and give blood samples. The goal is to understand the role of mitochondrial activity in bipolar disorder. Healthy volunteers who have never had a psychiatric disorder will have the same procedures, but they will not receive the medication.
Official title: Broadband Near Infrared Spectroscopy to Elucidate the of Role Cortical Brain Cytochrome C Oxidase Activity in the Pathophysiology of Bipolar Disorder
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2026-11-01
Completion Date
2028-07-30
Last Updated
2026-09-08
Healthy Volunteers
Yes
Conditions
Interventions
Lurasidone (Latuda)
The medication will be used to understand how the imaging signal changes when symptoms change during treatment.
Locations (1)
New York State Psychiatric Institute
New York, New York, United States