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COMPLETED
NCT07807709

Evaluation of Jugular Venous Distensibility Index in Intravascular Fluid Management and Comparison of the Effectiveness of Noninvasive and Minimally Invasive Methods

Sponsor: Gaziosmanpasa Research and Education Hospital

View on ClinicalTrials.gov

Summary

Assessment of intravascular volume status is an important component of hemodynamic management in critically ill patients. Several noninvasive and minimally invasive parameters, including the pleth variability index (PVI), pulse pressure variation (PPV), stroke volume variation (SVV), and ultrasonographic measurements of venous diameter variation, can be used for this purpose. Although the inferior vena cava distensibility index (IVC-DI) is commonly evaluated using ultrasonography, visualization of the inferior vena cava may be technically difficult or time-consuming in some patients. The right internal jugular vein is more superficial and may therefore provide a faster and more accessible alternative. The primary aim of this prospective observational study is to evaluate the correlation and agreement between the right internal jugular vein distensibility index (RJV-DI) and IVC-DI in mechanically ventilated adult intensive care unit patients. The secondary aims are to compare the correlations of RJV-DI and IVC-DI with PVI, PPV, and SVV and to compare the acquisition times of the two ultrasonographic measurements. The study will assess whether RJV-DI may provide a practical and faster alternative for hemodynamic assessment, particularly when visualization of the inferior vena cava is difficult.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

82

Start Date

2024-01-01

Completion Date

2024-08-01

Last Updated

2026-09-08

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

Pleth variability index

Pleth variability index

DIAGNOSTIC_TEST

Pulse pressure variation

Pulse pressure variation

DIAGNOSTIC_TEST

Stroke volume variation

Stroke volume variation

DIAGNOSTIC_TEST

Right jugular vein distensibility index

Right jugular vein distensibility index

DIAGNOSTIC_TEST

Inferior Vena Cava Distensibility Index

Inferior Vena Cava Distensibility Index

Locations (1)

Gaziosmanpasa Training Research Hospital

Istanbul, Turkey (Türkiye)