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Trace Element Imbalances in Dialysis Patients With CKD: the Role of Hemodialysis
Sponsor: Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Summary
Chronic kidney disease (CKD) is associated with alterations in the balance of trace elements and metals, which may result from reduced dietary intake, impaired renal function, dialysis-related removal, or environmental exposure. Hemodialysis may play a relevant role in both the removal and potential introduction of these elements. This pilot study aims to investigate trace element and metal imbalances in older patients with advanced CKD and to assess the influence of bicarbonate hemodialysis and dialysis-related environmental exposure on their elemental profile.
Official title: Trace Element Imbalances in Patients With Chronic Kidney Disease (CKD) Undergoing Dialysis: the Role of Hemodialysis Treatment as an Environmental Factor
Key Details
Gender
All
Age Range
60 Years - Any
Study Type
OBSERVATIONAL
Enrollment
20
Start Date
2025-03-31
Completion Date
2026-03-31
Last Updated
2026-09-09
Healthy Volunteers
No
Conditions
Interventions
Compare blood concentrations of selected trace elements and metals before and after hemodialysis
The main objective is to compare blood concentrations of selected trace elements and metals before and after hemodialysis in incident and prevalent patients. The elements investigated will include zinc, copper, manganese, lead, aluminum, mercury, selenium, cadmium and chromium. The study will also investigate whether the elemental profile differs according to the duration of exposure to hemodialysis.
Locations (1)
SCDU Nefrologia e Dialisi
Alessandria, Alessandria, Italy