Clinical Research Directory

Inclusion Criteria: * Aged18-40 years, inclusive. * Body mass index (BMI) of 25-40 kg/m², inclusive. * Meeting the 2003 Rotterdam diagnostic criteria for polycystic ovary syndrome (PCOS), defined by the presence of at least two of the following three criteria: Oligo-ovulation or anovulation; Clinical and/or biochemical signs of hyperandrogenism; Polycystic ovarian morphology on ultrasonography. * Willing to participate voluntarily in the study, able to understand the study procedures, and able to provide written informed consent. Exclusion Criteria: * Presence of hyperandrogenemia due to other causes, such as hyperprolactinemia, thyroid disorders, congenital adrenal hyperplasia, or exogenous androgen use. * Presence of renal disease (creatinine clearance \<60 mL/min), hepatic impairment, autoimmune disease, or malignancy. * Type 1 diabetes mellitus or glycated hemoglobin (HbA1c) \>53 mmol/mol (7%). - Use, within the past 3 months, of medications that may affect study assessments, including glucocorticoids, insulin, glucose-lowering agents such as acarbose, antidepressants, hormonal contraceptives, ovulation-inducing agents, or other relevant medications. * Blood pressure \>160/100 mmHg. * Currently pregnant or breastfeeding, pregnancy within the past 6 months, or planning to become pregnant during the study period. * Having received continuous acupuncture treatment for at least 2 months prior to study treatment. * Daily smoking or alcohol consumption. * Presence of language barriers, psychiatric disorders, or other conditions that may impair the participant's ability to understand the study, comply with the intervention, or complete follow-up assessments.