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COMPLETED
NCT07810127
NA

EXPLORATORY STUDY OF THE POTENTIAL OF THERAPEUTIC EXERCISE IN THE TREATMENT OF WILLIS-EKBOM DISEASE

Sponsor: Universidad Pontificia Comillas

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to learn whether a home-based therapeutic exercise program can improve symptoms of restless legs syndrome (RLS), also known as Willis-Ekbom disease, in adults with chronic RLS. It will also assess whether the program affects daytime sleepiness and quality of life, and whether participants can follow and tolerate the exercises. The main questions it aims to answer are: * Does a myofascial self-stretching routine improve RLS symptoms? * Does the exercise program affect daytime sleepiness and quality of life? Researchers will compare two low-risk home exercise routines: a myofascial self-stretching program based on Mézières and Global Active Stretching principles and Buerger-Allen exercises. Participants will be assigned to one of two exercise sequences and will complete their routine over 2 weeks. Participants will: * complete a clinical assessment at the start and end of the study; * perform a 10- to 20-minute exercise session at home each night, preferably before bedtime; * record their RLS symptoms each day; and * keep their usual RLS medication stable during the study.

Official title: Estudio Exploratorio Del Potencial Del Ejercicio Terapeútico en el Tratamiento de la Enfermedad de Willis-Ekbom

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

27

Start Date

2026-03-03

Completion Date

2026-07-22

Last Updated

2026-09-09

Healthy Volunteers

No

Interventions

BEHAVIORAL

Myofascial Self-Stretching Exercise Program

Participants perform a home-based myofascial self-stretching exercise program derived from the Mézières therapeutic approach and Global Active Stretching. The program combines sustained low-load activation of agonist muscles, sustained low-intensity stretching of antagonist muscles, controlled breathing with emphasis on expiration, and postural and attentional control. The exercises are performed progressively according to each participant's capabilities. Each session lasts approximately 15 to 20 minutes and is performed in the evening, preferably shortly before bedtime.

BEHAVIORAL

Buerger-Allen Exercise Program

Participants perform a home-based Buerger-Allen exercise program consisting of a sequence of three exercises involving changes in lower-limb position and repeated ankle movements. The routine includes ankle flexion-extension movements with the legs elevated, circular ankle movements while seated with the legs hanging, and repeated ankle flexion-extension movements while lying down. Each exercise is performed for approximately 3 to 5 minutes, resulting in a total session duration of approximately 10 to 15 minutes. The sessions are performed in the evening, preferably shortly before bedtime.

Locations (1)

Asociación Española de Piernas Inquietas (AESPI)

Madrid, Spain