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Using Bedside Ultrasound to Understand Fluid Management in Patients With Chronic Liver Disease
Sponsor: Royal Free Hospital NHS Foundation Trust
Summary
The goal of this observational study is to see if repeated bedside ultrasound measurements of the lungs and abdomen as well as a blood vessel in the neck can be done in patients with advanced liver disease and ascites (fluid in the abdomen) on hospital wards and day case units. We will also learn about how patients view this test. The main questions it will answer are: How long does it take to do the measurements? How often are we able to get all the measurements we are trying to do? How do patients feel about having this test done? For patients in the study this will involve: Undergoing ultrasound scans of the neck, chest and abdomen on at least one occasion during hospital admission, and up to a maximum of five times in a day. An extra blood test may be taken at the same time as usual blood tests taken during the hospital stay. A brief questionnaire about their experience of having the test.
Official title: POCUS Guided Fluid Resuscitation in Cirrhosis
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2026-09-01
Completion Date
2027-04
Last Updated
2026-09-09
Healthy Volunteers
No
Conditions
Interventions
Ultrasound measurement
Point-of-care ultrasound measurements of the IJV, IVC, thorax and abdomen performed at least once following recruitments and on up to three separate occasions in total during the first seven days of admission, with up to five measurements in total on each occasion.
Blood draw for the laboratory assessment
A blood sample for research analysis may be taken at the same time as standard of care blood tests during the study.