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Breast and Vascular Effects of Menopausal Hormone Therapy in Postmenopausal Women
Sponsor: Sanliurfa Mehmet Akif Inan Education and Research Hospital
Summary
This prospective, single-center, observational controlled cohort study aims to evaluate the effects of menopausal hormone therapy (MHT) on breast imaging findings and carotid intima-media thickness in postmenopausal women. A total of 120 postmenopausal women will be enrolled. Participants will be observed in two groups according to their clinical management: women receiving systemic menopausal hormone therapy (n=70) and women not receiving systemic menopausal hormone therapy (n=50). Breast imaging findings, breast density, menopausal symptoms, endometrial findings, cardiometabolic parameters, and carotid intima-media thickness will be prospectively evaluated during a 12-month follow-up period.
Official title: Prospective Evaluation of the Effects of Menopausal Hormone Therapy on Breast Imaging Findings and Carotid Intima-Media Thickness in Postmenopausal Women
Key Details
Gender
FEMALE
Age Range
45 Years - 60 Years
Study Type
OBSERVATIONAL
Enrollment
120
Start Date
2026-06-01
Completion Date
2027-05-31
Last Updated
2026-09-09
Healthy Volunteers
No
Conditions
Interventions
Menopausal Hormone Therapy
Systemic menopausal hormone therapy prescribed as part of routine clinical care according to individual clinical indications. Treatment is not assigned by the study protocol.
Locations (1)
Acıbadem Bursa Hospital
Bursa, Turkey (Türkiye)