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Preconception vs First-Trimester Screening and Treatment for Iron Deficiency Anemia: A Cluster Randomized Trial
Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Summary
This cluster randomized trial compares preconception with early-pregnancy anemia screening and iron supplementation, assessing late pregnancy iron deficiency anemia and maternal and infant outcomes.
Official title: Effect of Anemia Intervention Timing (Preconception vs. First Trimester) on the Control of Iron Deficiency Anemia in the Third Trimester: A Cluster Randomized Controlled Trial
Key Details
Gender
FEMALE
Age Range
18 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
960
Start Date
2026-07-10
Completion Date
2029-07
Last Updated
2026-09-10
Healthy Volunteers
Yes
Conditions
Interventions
Preconception Anemia Screening and Treatment Strategy
Women planning pregnancy within 6 months undergo hemoglobin, hemoglobin electrophoresis, and serum ferritin assessments before conception. Those with hemoglobin levels below 120 g/L and/or serum ferritin levels below 30 μg/L receive oral ferrous succinate (0.2 g twice daily) plus vitamin C, with scheduled hematologic monitoring.
Early-Pregnancy Anemia Screening and Treatment Strategy
Women with a singleton pregnancy at 12 weeks' gestation who have hemoglobin levels below 110 g/L and/or serum ferritin levels below 30 μg/L will receive oral ferrous succinate (0.2 g twice daily) plus vitamin C, with scheduled hematologic monitoring
Locations (1)
Yanjin County Maternal and Child Health Hospital
Zhaotong, Yunnan, China