Clinical Research Directory

Inclusion Criteria: 1. Women aged 20-40 years; 2. Body Mass Index(BMI) ≥ 28kg/m2; 3. Women who intend to undergo frozen-thawed embryo transfer; 4. At least one embryo available for transfer; 5. Be capable of giving informed consent. Exclusion Criteria: 1. Women who have been diagnosed with diseases affecting uterine cavity or endometrial receptivity; 2. Presence of endocrine disorders that may significantly affect body weight; 3. Use of drugs that may cause significant weight changes within 8 weeks before screening; 4. Presence of contraindications to the use of dual GIP/GLP-1 receptor agonist; 5. Previous bariatric surgery (e.g., gastric bypass) or planning to undergo such surgery during the study period; 6. Serum triglycerides (TG) \> 5.64mmol/L; 7. Calcitonin≥50 ng/L; 8. Presence of medical contraindications to assisted reproductive technology and/or pregnancy; 9. Any other condition considered inappropriate for participation by the investigator.