Clinical Research Directory

Insulin Eye Drops and Epithelial Healing After Corneal Cross-linking

Sponsor: Cairo University

Summary

The goal of this clinical trial was to learn if topical insulin eye drops affected corneal epithelial wound healing after corneal collagen cross-linking. The main questions it aimed to answer were: Does topical insulin accelerate corneal epithelial healing after corneal collagen cross-linking? Does it affect post-operative pain? Participants were all diagnosed as having bilateral progressive Keratoconus and were already scheduled for bilateral cross-linking: Post-operatively, they were asked to apply insulin eye drops in one eye only (4 times daily) in addition to the prescribed routine post-operative treatment which was applied to both eyes. They were also asked to come for follow-up visits on post-operative day 1,2,3,5 and 7 or until complete corneal wound healing. The epithelial defect was measured in each eye and the participants were asked to report the degree of pain they felt in each eye at each visit until complete epithelial healing.

Official title: The Effect of Topical Insulin Eye Drops On Corneal Epithelial Wound Healing After Corneal Collagen Cross-linking in Keratoconus Management: A Paired-Eye Study

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Interventions

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